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Recombinant human bone morphogenetic protein 2 and 7 inhibit the degeneration of intervertebral discs by blocking the Puma-dependent apoptotic signaling

Recombinant human bone morphogenetic proteins (rhBMPs) can stimulate bone formation and growth in the treatment of spinal fusions and nonunions. However, it is still unclear whether rhBMPs function in the prevention of intervertebral disc degeneration (IDD). Here, we discovered that BMP levels were...

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Detalles Bibliográficos
Autores principales: Xie, Shiwei, Zhao, Chenyang, Chen, Wei, Li, Gengwu, Xiong, Zhiwei, Tang, Xiangjun, Zhang, Fan, Xiao, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241732/
https://www.ncbi.nlm.nih.gov/pubmed/34239363
http://dx.doi.org/10.7150/ijbs.56823