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Recombinant human bone morphogenetic protein 2 and 7 inhibit the degeneration of intervertebral discs by blocking the Puma-dependent apoptotic signaling
Recombinant human bone morphogenetic proteins (rhBMPs) can stimulate bone formation and growth in the treatment of spinal fusions and nonunions. However, it is still unclear whether rhBMPs function in the prevention of intervertebral disc degeneration (IDD). Here, we discovered that BMP levels were...
Autores principales: | Xie, Shiwei, Zhao, Chenyang, Chen, Wei, Li, Gengwu, Xiong, Zhiwei, Tang, Xiangjun, Zhang, Fan, Xiao, Heng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241732/ https://www.ncbi.nlm.nih.gov/pubmed/34239363 http://dx.doi.org/10.7150/ijbs.56823 |
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