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Structural mechanism of laminin recognition by integrin

Recognition of laminin by integrin receptors is central to the epithelial cell adhesion to basement membrane, but the structural background of this molecular interaction remained elusive. Here, we report the structures of the prototypic laminin receptor α6β1 integrin alone and in complex with three-...

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Detalles Bibliográficos
Autores principales: Arimori, Takao, Miyazaki, Naoyuki, Mihara, Emiko, Takizawa, Mamoru, Taniguchi, Yukimasa, Cabañas, Carlos, Sekiguchi, Kiyotoshi, Takagi, Junichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241838/
https://www.ncbi.nlm.nih.gov/pubmed/34188035
http://dx.doi.org/10.1038/s41467-021-24184-8