The bacterial toxin ExoU requires a host trafficking chaperone for transportation and to induce necrosis

Pseudomonas aeruginosa can cause nosocomial infections, especially in ventilated or cystic fibrosis patients. Highly pathogenic isolates express the phospholipase ExoU, an effector of the type III secretion system that acts on plasma membrane lipids, causing membrane rupture and host cell necrosis....

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Detalles Bibliográficos
Autores principales: Deruelle, Vincent, Bouillot, Stéphanie, Job, Viviana, Taillebourg, Emmanuel, Fauvarque, Marie-Odile, Attrée, Ina, Huber, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241856/
https://www.ncbi.nlm.nih.gov/pubmed/34188051
http://dx.doi.org/10.1038/s41467-021-24337-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241856/
https://www.ncbi.nlm.nih.gov/pubmed/34188051
http://dx.doi.org/10.1038/s41467-021-24337-9

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