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A Bayesian semi-parametric model for thermal proteome profiling

The thermal stability of proteins can be altered when they interact with small molecules, other biomolecules or are subject to post-translation modifications. Thus monitoring the thermal stability of proteins under various cellular perturbations can provide insights into protein function, as well as...

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Detalles Bibliográficos
Autores principales: Fang, Siqi, Kirk, Paul D. W., Bantscheff, Marcus, Lilley, Kathryn S., Crook, Oliver M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241860/
https://www.ncbi.nlm.nih.gov/pubmed/34188175
http://dx.doi.org/10.1038/s42003-021-02306-8