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Neu1 deficiency induces abnormal emotional behavior in zebrafish

NEU1 sialidase hydrolyzes sialic acids from glycoconjugates in lysosomes. Deficiency of NEU1 causes sialidosis with symptoms including facial dysmorphism, bone dysplasia, and neurodegeneration. However, the effects of NEU1 deficiency on emotional activity have not been explored. Here, we conducted t...

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Detalles Bibliográficos
Autores principales: Ikeda, Asami, Komamizu, Mayu, Hayashi, Akito, Yamasaki, Chiharu, Okada, Keiji, Kawabe, Momoko, Komatsu, Masaharu, Shiozaki, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241872/
https://www.ncbi.nlm.nih.gov/pubmed/34188220
http://dx.doi.org/10.1038/s41598-021-92778-9