Molecular insights on ABL kinase activation using tree-based machine learning models and molecular docking

Abelson kinase (c-Abl) is a non-receptor tyrosine kinase involved in several biological processes essential for cell differentiation, migration, proliferation, and survival. This enzyme's activation might be an alternative strategy for treating diseases such as neutropenia induced by chemothera...

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Detalles Bibliográficos
Autores principales: Fernandes, Philipe Oliveira, Martins, Diego Magno, de Souza Bozzi, Aline, Martins, João Paulo A., de Moraes, Adolfo Henrique, Maltarollo, Vinícius Gonçalves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241884/
https://www.ncbi.nlm.nih.gov/pubmed/34191245
http://dx.doi.org/10.1007/s11030-021-10261-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241884/
https://www.ncbi.nlm.nih.gov/pubmed/34191245
http://dx.doi.org/10.1007/s11030-021-10261-z

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