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Terminal uridyltransferase 7 regulates TLR4-triggered inflammation by controlling Regnase-1 mRNA uridylation and degradation

Different levels of regulatory mechanisms, including posttranscriptional regulation, are needed to elaborately regulate inflammatory responses to prevent harmful effects. Terminal uridyltransferase 7 (TUT7) controls RNA stability by adding uridines to its 3′ ends, but its function in innate immune r...

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Detalles Bibliográficos
Autores principales: Lin, Chia-Ching, Shen, Yi-Ru, Chang, Chi-Chih, Guo, Xiang-Yi, Young, Yun-Yun, Lai, Ting-Yu, Yu, I-Shing, Lee, Chih-Yuan, Chuang, Tsung-Hsien, Tsai, Hsin-Yue, Hsu, Li-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241994/
https://www.ncbi.nlm.nih.gov/pubmed/34188032
http://dx.doi.org/10.1038/s41467-021-24177-7