Cell wall integrity is compromised under temperature stress in Schizosaccharomyces pombe expressing a valproic acid-sensitive vas4 mutant

Valproic acid (VPA) is widely used as a eutherapeutic and safe anticonvulsant drug, but the mechanism is not well elucidated. Histone deacetylases (HDACs) were first identified as direct targets of VPA. Many loss-of function mutants in S. pombe have been shown to be VPA sensitive but not sensitive t...

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Detalles Bibliográficos
Autores principales: Qiao, Sen, Luo, Xiaofang, Wang, Hui, Fang, Yue, Zhang, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242086/
https://www.ncbi.nlm.nih.gov/pubmed/34188069
http://dx.doi.org/10.1038/s41598-021-92466-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242086/
https://www.ncbi.nlm.nih.gov/pubmed/34188069
http://dx.doi.org/10.1038/s41598-021-92466-8

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