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Ultrasonic microbubble VEGF gene delivery improves angiogenesis of senescent endothelial progenitor cells

The therapeutic effects of ultrasonic microbubble transfection (UMT)-based vascular endothelial growth factor 165 (VEGF165) gene delivery on young and senescent endothelial progenitor cells (EPCs) were investigated. By UMT, plasmid DNA (pDNA) can be delivered into both young EPCs and senescent EPCs....

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Detalles Bibliográficos
Autores principales: Lee, Yi-Nan, Wu, Yih-Jer, Lee, Hsin-I., Wang, Hsueh-Hsiao, Chang, Chiung-Yin, Tien, Ting-Yi, Lin, Chao-Feng, Su, Cheng-Huang, Yeh, Hung-I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242093/
https://www.ncbi.nlm.nih.gov/pubmed/34188086
http://dx.doi.org/10.1038/s41598-021-92754-3