Serine residues 726 and 780 have nonredundant roles regulating STAT5a activity in luminal breast cancer

In breast cancer, prolactin-induced activation of the transcription factor STAT5a results from the phosphorylation of STAT5a tyrosine residue 694. However, its role in mammary oncogenesis remains an unsettled debate as STAT5a exhibits functional dichotomy with both pro-differentiative and pro-prolif...

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Detalles Bibliográficos
Autores principales: Woock, Alicia E., Grible, Jacqueline M., Olex, Amy L., Harrell, J. Chuck, Zot, Patricija, Idowu, Michael, Clevenger, Charles V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242097/
https://www.ncbi.nlm.nih.gov/pubmed/34188118
http://dx.doi.org/10.1038/s41598-021-92830-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242097/
https://www.ncbi.nlm.nih.gov/pubmed/34188118
http://dx.doi.org/10.1038/s41598-021-92830-8

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