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Serine residues 726 and 780 have nonredundant roles regulating STAT5a activity in luminal breast cancer
In breast cancer, prolactin-induced activation of the transcription factor STAT5a results from the phosphorylation of STAT5a tyrosine residue 694. However, its role in mammary oncogenesis remains an unsettled debate as STAT5a exhibits functional dichotomy with both pro-differentiative and pro-prolif...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242097/ https://www.ncbi.nlm.nih.gov/pubmed/34188118 http://dx.doi.org/10.1038/s41598-021-92830-8 |