Cargando…

Analysis of Methylation Dynamics Reveals a Tissue-Specific, Age-Dependent Decline in 5-Methylcytosine Within the Genome of the Vertebrate Aging Model Nothobranchius furzeri

Erosion of the epigenetic DNA methylation landscape is a widely recognized hallmark of aging. Emerging advances in high throughput sequencing techniques, in particular DNA methylation data analysis, have resulted in the establishment of precise human and murine age prediction tools. In vertebrates,...

Descripción completa

Detalles Bibliográficos
Autores principales: Zupkovitz, Gordin, Kabiljo, Julijan, Kothmayer, Michael, Schlick, Katharina, Schöfer, Christian, Lagger, Sabine, Pusch, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242171/
https://www.ncbi.nlm.nih.gov/pubmed/34222326
http://dx.doi.org/10.3389/fmolb.2021.627143