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The ETS Inhibitor YK-4-279 Suppresses Thyroid Cancer Progression Independent of TERT Promoter Mutations

Hotspot mutations in the core promoter region of the telomerase reverse transcriptase (TERT) gene have been well established to associate with aggressive clinical characteristics, radioiodine refractory, tumor recurrence, and mortality in thyroid cancer. Several E-twenty-six (ETS) transcription fact...

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Detalles Bibliográficos
Autores principales: Xue, Junyu, Li, Shiyong, Shi, Peijie, Chen, Mengke, Yu, Shuang, Hong, Shubin, Li, Yanbing, Liu, Rengyun, Xiao, Haipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242932/
https://www.ncbi.nlm.nih.gov/pubmed/34221969
http://dx.doi.org/10.3389/fonc.2021.649323