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Significance of PD1 Alternative Splicing in Celiac Disease as a Novel Source for Diagnostic and Therapeutic Target

BACKGROUND: We have focused on the alteration of the PD-1/PD-L1 pathway in celiac disease and discussed the roles of the PD1 pathway in regulating the immune response. We explored the idea that the altered mRNA splicing process in key regulatory proteins could represent a novel source to identify di...

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Detalles Bibliográficos
Autores principales: Ponce de León, Candelaria, Lorite, Pedro, López-Casado, Miguel Ángel, Barro, Francisco, Palomeque, Teresa, Torres, María Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8242946/
https://www.ncbi.nlm.nih.gov/pubmed/34220824
http://dx.doi.org/10.3389/fimmu.2021.678400