IL-4-Responsive B Cells Are Detrimental During Chronic Tuberculosis Infection in Mice

In tuberculosis, T cell-mediated immunity is extensively studied whilst B cells received limited attention in human and mice. Of interest, Mycobacterium tuberculosis (Mtb) does increase IL-4 Receptor-alpha (IL4Rα) expression in murine B cells. To better understand the role of IL4Rα signalling in B c...

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Detalles Bibliográficos
Autores principales: Parihar, Suraj P., Ozturk, Mumin, Höft, Maxine A., Chia, Julius E., Guler, Reto, Keeton, Roanne, van Rensburg, Ilana C., Loxton, Andre G., Brombacher, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243286/
https://www.ncbi.nlm.nih.gov/pubmed/34220793
http://dx.doi.org/10.3389/fimmu.2021.611673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243286/
https://www.ncbi.nlm.nih.gov/pubmed/34220793
http://dx.doi.org/10.3389/fimmu.2021.611673

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