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IL-4-Responsive B Cells Are Detrimental During Chronic Tuberculosis Infection in Mice
In tuberculosis, T cell-mediated immunity is extensively studied whilst B cells received limited attention in human and mice. Of interest, Mycobacterium tuberculosis (Mtb) does increase IL-4 Receptor-alpha (IL4Rα) expression in murine B cells. To better understand the role of IL4Rα signalling in B c...
Autores principales: | Parihar, Suraj P., Ozturk, Mumin, Höft, Maxine A., Chia, Julius E., Guler, Reto, Keeton, Roanne, van Rensburg, Ilana C., Loxton, Andre G., Brombacher, Frank |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243286/ https://www.ncbi.nlm.nih.gov/pubmed/34220793 http://dx.doi.org/10.3389/fimmu.2021.611673 |
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