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Cannabinoid receptor 2 deficiency enhances isoflurane-induced spatial cognitive impairment in adult mice by affecting neuroinflammation, neurogenesis and neuroplasticity

Isoflurane (Iso) is a commonly used inhalational anesthetic and is associated with the incidence of postoperative cognitive dysfunction (POCD). Cannabinoid receptor 2 (CB2R) was previously reported to have a promising neuroprotective function in cases of POCD, but the specific mechanisms have remain...

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Detalles Bibliográficos
Autores principales: Li, Chao, Shi, Jingpu, Sun, Jiaguang, Shi, Yuanyuan, Jia, Huiqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243338/
https://www.ncbi.nlm.nih.gov/pubmed/34257720
http://dx.doi.org/10.3892/etm.2021.10340