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Prospective multicenter evaluation of real time PCR Kit prototype for early diagnosis of congenital Chagas disease

BACKGROUND: Current algorithm for Congenital Chagas Disease (cCD) diagnosis is unsatisfactory due to low sensitivity of the parasitological methods. Moreover, loss to follow-up precludes final serodiagnosis after nine months of life in many cases. A duplex TaqMan qPCR kit for Trypanosoma cruzi DNA a...

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Detalles Bibliográficos
Autores principales: Benatar, Alejandro Francisco, Danesi, Emmaría, Besuschio, Susana Alicia, Bortolotti, Santiago, Cafferata, María Luisa, Ramirez, Juan Carlos, Albizu, Constanza Lopez, Scollo, Karenina, Baleani, María, Lara, Laura, Agolti, Gustavo, Seu, Sandra, Adamo, Elsa, Lucero, Raúl Horacio, Irazu, Lucía, Rodriguez, Marcelo, Poeylaut-Palena, Andrés, Longhi, Silvia Andrea, Esteva, Mónica, Althabe, Fernando, Rojkin, Federico, Bua, Jacqueline, Sosa-Estani, Sergio, Schijman, Alejandro Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243352/
https://www.ncbi.nlm.nih.gov/pubmed/34186488
http://dx.doi.org/10.1016/j.ebiom.2021.103450