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Circular RNA circRHOBTB3 is downregulated in hepatocellular carcinoma and suppresses cell proliferation by inhibiting miR-18a maturation

BACKGROUND: Circular RNA circRHOBTB3 has been characterized as a tumor suppressor in gastric cancer, while its role in hepatocellular carcinoma (HCC) is unknown. This study was carried out to analyze the role of circRHOBTB3 in HCC. METHODS: In this study, circRHOBTB3, mature miR-18a, and miR-18a pre...

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Detalles Bibliográficos
Autores principales: Hu, Gang, Zhai, Shusen, Yu, Sheng, Huang, Zhen, Gao, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243428/
https://www.ncbi.nlm.nih.gov/pubmed/34187598
http://dx.doi.org/10.1186/s13027-021-00384-1