Menopausal symptoms are associated with oral sensory complaints in perimenopausal women: an observational study
BACKGROUND: Perimenopausal women experience a wide variety of systemic symptoms: hot flashes, sweating, mental health concerns and various oral sensory complaints (OSC). OSC in perimenopausal women include xerostomia, taste disturbance and burning mouth. However, the factors associated with these OS...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243452/ https://www.ncbi.nlm.nih.gov/pubmed/34193118 http://dx.doi.org/10.1186/s12905-021-01401-6 |
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author | Taga, Tomoharu Ito, Kayoko Takamatsu, Kiyoshi Ogawa, Mariko Funayama, Saori Inoue, Makoto |
author_facet | Taga, Tomoharu Ito, Kayoko Takamatsu, Kiyoshi Ogawa, Mariko Funayama, Saori Inoue, Makoto |
author_sort | Taga, Tomoharu |
collection | PubMed |
description | BACKGROUND: Perimenopausal women experience a wide variety of systemic symptoms: hot flashes, sweating, mental health concerns and various oral sensory complaints (OSC). OSC in perimenopausal women include xerostomia, taste disturbance and burning mouth. However, the factors associated with these OSC have not been identified. The purpose of this investigation was to elucidate the factors associated with OSC in perimenopausal women. METHODS: The study cohort comprised 43 perimenopausal women aged 45–55 years. Data on medical history, medications, menstrual status, menopausal symptoms, quality of life, xerostomia, taste disturbance and burning mouth were collected. Volumes of unstimulated and stimulated saliva were measured. Tongue coating was evaluated according to a tongue coating index. Univariate analysis was performed to identify factors significantly associated with having xerostomia, taste disturbance, burning mouth and more than two OSC (2OSC). Next, the factors strongly associated with these symptoms were examined by logistic regression analysis. RESULTS: The number of menopausal symptoms was significantly higher, and volume of unstimulated saliva was significantly lower in participants with xerostomia, taste disturbance, burning mouth or 2OSC than in those without these characteristics. Agents targeting the central nervous system were more frequently taken by participants with burning mouth and 2OSC than by those without these characteristics. According to logistic regression analysis, the number of menopausal symptoms was an explanatory variable for xerostomia, taste disturbance, burning mouth and 2OSC. CONCLUSIONS: Our findings suggested that OSC associated with the number of menopausal symptoms. Management of menopausal symptoms may decrease OSC, leading to improved quality of life of perimenopausal women. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12905-021-01401-6. |
format | Online Article Text |
id | pubmed-8243452 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-82434522021-06-30 Menopausal symptoms are associated with oral sensory complaints in perimenopausal women: an observational study Taga, Tomoharu Ito, Kayoko Takamatsu, Kiyoshi Ogawa, Mariko Funayama, Saori Inoue, Makoto BMC Womens Health Research BACKGROUND: Perimenopausal women experience a wide variety of systemic symptoms: hot flashes, sweating, mental health concerns and various oral sensory complaints (OSC). OSC in perimenopausal women include xerostomia, taste disturbance and burning mouth. However, the factors associated with these OSC have not been identified. The purpose of this investigation was to elucidate the factors associated with OSC in perimenopausal women. METHODS: The study cohort comprised 43 perimenopausal women aged 45–55 years. Data on medical history, medications, menstrual status, menopausal symptoms, quality of life, xerostomia, taste disturbance and burning mouth were collected. Volumes of unstimulated and stimulated saliva were measured. Tongue coating was evaluated according to a tongue coating index. Univariate analysis was performed to identify factors significantly associated with having xerostomia, taste disturbance, burning mouth and more than two OSC (2OSC). Next, the factors strongly associated with these symptoms were examined by logistic regression analysis. RESULTS: The number of menopausal symptoms was significantly higher, and volume of unstimulated saliva was significantly lower in participants with xerostomia, taste disturbance, burning mouth or 2OSC than in those without these characteristics. Agents targeting the central nervous system were more frequently taken by participants with burning mouth and 2OSC than by those without these characteristics. According to logistic regression analysis, the number of menopausal symptoms was an explanatory variable for xerostomia, taste disturbance, burning mouth and 2OSC. CONCLUSIONS: Our findings suggested that OSC associated with the number of menopausal symptoms. Management of menopausal symptoms may decrease OSC, leading to improved quality of life of perimenopausal women. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12905-021-01401-6. BioMed Central 2021-06-30 /pmc/articles/PMC8243452/ /pubmed/34193118 http://dx.doi.org/10.1186/s12905-021-01401-6 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Taga, Tomoharu Ito, Kayoko Takamatsu, Kiyoshi Ogawa, Mariko Funayama, Saori Inoue, Makoto Menopausal symptoms are associated with oral sensory complaints in perimenopausal women: an observational study |
title | Menopausal symptoms are associated with oral sensory complaints in perimenopausal women: an observational study |
title_full | Menopausal symptoms are associated with oral sensory complaints in perimenopausal women: an observational study |
title_fullStr | Menopausal symptoms are associated with oral sensory complaints in perimenopausal women: an observational study |
title_full_unstemmed | Menopausal symptoms are associated with oral sensory complaints in perimenopausal women: an observational study |
title_short | Menopausal symptoms are associated with oral sensory complaints in perimenopausal women: an observational study |
title_sort | menopausal symptoms are associated with oral sensory complaints in perimenopausal women: an observational study |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243452/ https://www.ncbi.nlm.nih.gov/pubmed/34193118 http://dx.doi.org/10.1186/s12905-021-01401-6 |
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