A protocol for representative sampling of solid tumors to improve the accuracy of sequencing results

Owing to spatial segregation of tumor subclones, solid tumor sampling using formalin-fixed, paraffin-embedded blocks is often inadequate to represent the genomic heterogeneity of solid tumors. We present an approach, representative sampling, to dissect and homogenize leftover residual surgical tissu...

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Detalles Bibliográficos
Autores principales: Gallegos, Lisa L., Gilchrist, Ashley, Spain, Lavinia, Stanislaw, Stacey, Hill, Samantha M., Primus, Vanessa, Jones, Carol, Agrawal, Somya, Tippu, Zayd, Barhoumi, Aoune, Noel-Storr, Glenn, Alexander, Nelson R., Turajlic, Samra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243513/
https://www.ncbi.nlm.nih.gov/pubmed/34223198
http://dx.doi.org/10.1016/j.xpro.2021.100624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243513/
https://www.ncbi.nlm.nih.gov/pubmed/34223198
http://dx.doi.org/10.1016/j.xpro.2021.100624

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