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A protocol for representative sampling of solid tumors to improve the accuracy of sequencing results
Owing to spatial segregation of tumor subclones, solid tumor sampling using formalin-fixed, paraffin-embedded blocks is often inadequate to represent the genomic heterogeneity of solid tumors. We present an approach, representative sampling, to dissect and homogenize leftover residual surgical tissu...
Autores principales: | Gallegos, Lisa L., Gilchrist, Ashley, Spain, Lavinia, Stanislaw, Stacey, Hill, Samantha M., Primus, Vanessa, Jones, Carol, Agrawal, Somya, Tippu, Zayd, Barhoumi, Aoune, Noel-Storr, Glenn, Alexander, Nelson R., Turajlic, Samra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243513/ https://www.ncbi.nlm.nih.gov/pubmed/34223198 http://dx.doi.org/10.1016/j.xpro.2021.100624 |
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