Hepatocyte-specific glucose-6-phosphatase deficiency disturbs platelet aggregation and decreases blood monocytes upon fasting-induced hypoglycemia

OBJECTIVE: Glycogen storage disease type 1a (GSD Ia) is a rare inherited metabolic disorder caused by mutations in the glucose-6-phosphatase (G6PC1) gene. When untreated, GSD Ia leads to severe fasting-induced hypoglycemia. Although current intensive dietary management aims to prevent hypoglycemia,...

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Detalles Bibliográficos
Autores principales: La Rose, Anouk M., Bazioti, Venetia, Hoogerland, Joanne A., Svendsen, Arthur F., Groenen, Anouk G., van Faassen, Martijn, Rutten, Martijn G.S., Kloosterhuis, Niels J., Dethmers-Ausema, Bertien, Nijland, J. Hendrik, Mithieux, Gilles, Rajas, Fabienne, Kuipers, Folkert, Lukens, Michaël V., Soehnlein, Oliver, Oosterveer, Maaike H., Westerterp, Marit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243524/
https://www.ncbi.nlm.nih.gov/pubmed/34091064
http://dx.doi.org/10.1016/j.molmet.2021.101265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243524/
https://www.ncbi.nlm.nih.gov/pubmed/34091064
http://dx.doi.org/10.1016/j.molmet.2021.101265

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