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T-cell receptor-based therapy: an innovative therapeutic approach for solid tumors

T-cell receptor (TCR)-based adoptive therapy employs genetically modified lymphocytes that are directed against specific tumor markers. This therapeutic modality requires a structured and integrated process that involves patient screening (e.g., for HLA-A*02:01 and specific tumor targets), leukapher...

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Detalles Bibliográficos
Autores principales: Tsimberidou, Apostolia-Maria, Van Morris, Karlyle, Vo, Henry Hiep, Eck, Stephen, Lin, Yu-Feng, Rivas, Jorge Mauricio, Andersson, Borje S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243554/
https://www.ncbi.nlm.nih.gov/pubmed/34193217
http://dx.doi.org/10.1186/s13045-021-01115-0