Cargando…

T-cell receptor-based therapy: an innovative therapeutic approach for solid tumors

T-cell receptor (TCR)-based adoptive therapy employs genetically modified lymphocytes that are directed against specific tumor markers. This therapeutic modality requires a structured and integrated process that involves patient screening (e.g., for HLA-A*02:01 and specific tumor targets), leukapher...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tsimberidou, Apostolia-Maria, Van Morris, Karlyle, Vo, Henry Hiep, Eck, Stephen, Lin, Yu-Feng, Rivas, Jorge Mauricio, Andersson, Borje S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243554/ https://www.ncbi.nlm.nih.gov/pubmed/34193217 http://dx.doi.org/10.1186/s13045-021-01115-0

Ejemplares similares

First-in-Human Study of OBI-999, a Globo H-Targeting Antibody-Drug Conjugate, in Patients With Advanced Solid Tumors
por: Tsimberidou, Apostolia Maria, et al.
Publicado: (2023)

Clinical trial design in the era of precision medicine
por: Fountzilas, Elena, et al.
Publicado: (2022)

Prolonged response to treatment based on cell-free DNA analysis and molecular profiling in three patients with metastatic cancer: a case series
por: Naqvi, Mohammad Faraz, et al.
Publicado: (2021)

Dataset of phase I and II immunotherapy clinical trials used for a meta-analysis to assess the role of biomarkers in treatment outcomes in diverse cancers
por: Fountzilas, Elena, et al.
Publicado: (2023)

Reprogramming T cell differentiation and exhaustion in CAR-T cell therapy
por: Bulliard, Yannick, et al.
Publicado: (2023)

Precision Oncology: Evolving Clinical Trials across Tumor Types
por: Song, I-Wen, et al.
Publicado: (2023)

Expanded access to investigational drugs: balancing patient safety with potential therapeutic benefits
por: Fountzilas, Elena, et al.
Publicado: (2018)

Ipilimumab, Pembrolizumab, or Nivolumab in Combination with BBI608 in Patients with Advanced Cancers Treated at MD Anderson Cancer Center
por: Vo, Henry Hiep, et al.
Publicado: (2022)

AKT inhibition in the central nervous system induces signaling defects resulting in psychiatric symptomatology
por: Tsimberidou, Apostolia-Maria, et al.
Publicado: (2022)

Phase 1 dose-escalation study evaluating the safety, pharmacokinetics, and clinical activity of OBI-3424 in patients with advanced or metastatic solid tumors
por: Tsimberidou, Apostolia Maria, et al.
Publicado: (2023)

Dasatinib in chronic myeloid leukemia: a review
por: Aguilera, Dolly G, et al.
Publicado: (2009)

Circulating tumor DNA analysis in the era of precision oncology
por: Said, Rabih, et al.
Publicado: (2020)

Identification of novel therapeutic targets in the PI3K/AKT/mTOR pathway in hepatocellular carcinoma using targeted next generation sequencing
por: Janku, Filip, et al.
Publicado: (2014)

Phase 1 trial of ADI‐PEG 20 and liposomal doxorubicin in patients with metastatic solid tumors
por: Yao, Shuyang, et al.
Publicado: (2021)

Digital Therapeutics in Urology: An Innovative Approach to Patient Care and Management
por: Rodler, Severin, et al.
Publicado: (2023)

Selinexor in combination with standard chemotherapy in patients with advanced or metastatic solid tumors
por: Thein, Kyaw Z., et al.
Publicado: (2021)

The Origins and Generation of Cancer-Associated Mesenchymal Stromal Cells: An Innovative Therapeutic Target for Solid Tumors
por: Li, Wei, et al.
Publicado: (2021)

QSAR-Based Computational Approaches to Accelerate the Discovery of Sigma-2 Receptor (S2R) Ligands as Therapeutic Drugs
por: Yu, Yangxi, et al.
Publicado: (2021)

Dual EGFR blockade with cetuximab and erlotinib combined with anti-VEGF antibody bevacizumab in advanced solid tumors: a phase 1 dose escalation triplet combination trial
por: Subbiah, Vivek, et al.
Publicado: (2020)

Neurosyphilis With Concomitant Respiratory Failure: A Case Study and Treatment Considerations
por: Bistas, Karlyle, et al.
Publicado: (2023)

The Intricacies of Survivor's Guilt: Exploring Its Phenomenon Across Contexts
por: Bistas, Karlyle, et al.
Publicado: (2023)

Innovative Therapeutic Approaches for Duchenne Muscular Dystrophy
por: Fortunato, Fernanda, et al.
Publicado: (2021)

Engineering for Success: Approaches to Improve Chimeric Antigen Receptor T Cell Therapy for Solid Tumors
por: Mata, Melinda, et al.
Publicado: (2019)

Progressive multifocal leukoencephalopathy in a patient without apparent immunosuppression
por: Vaklavas, Christos, et al.
Publicado: (2010)

Next generation sequencing of carcinoma of unknown primary reveals novel combinatorial strategies in a heterogeneous mutational landscape
por: Subbiah, Ishwaria M., et al.
Publicado: (2017)

Phase I study of imalumab (BAX69), a fully human recombinant antioxidized macrophage migration inhibitory factor antibody in advanced solid tumours
por: Mahalingam, Devalingam, et al.
Publicado: (2020)

Selinexor in Combination with Carboplatin and Pemetrexed in Patients with Advanced or Metastatic Solid Tumors: Results of an Open-Label, Single-Center, Multi-Arm Phase 1b Study
por: Thein, Kyaw Z., et al.
Publicado: (2022)

Aboulomania, a Mental Disorder Characterized by Pathological Indecisiveness
por: Bistas, Karlyle, et al.
Publicado: (2023)

Neuropeptide S Receptor as an Innovative Therapeutic Target for Parkinson Disease
por: Holanda, Victor A. D., et al.
Publicado: (2021)

Selinexor in combination with carboplatin and paclitaxel in patients with advanced solid tumors: Results of a single-center, multi-arm phase Ib study
por: Thein, Kyaw Z., et al.
Publicado: (2021)

Correction to: Selinexor in combination with carboplatin and paclitaxel in patients with advanced solid tumors: results of a single‑center, multi‑arm phase Ib study
por: Thein, Kyaw Z., et al.
Publicado: (2021)

Overview of the role of nanotechnological innovations in the detection and treatment of solid tumors
por: Frank, Derusha, et al.
Publicado: (2014)

Combinatorial design of a sialic acid imprinted binding site exploring a dual ion receptor approach
por: Mavliutova, Liliia, et al.
Publicado: (2021)

The Benefits of Prebiotics and Probiotics on Mental Health
por: Bistas, Karlyle G, et al.
Publicado: (2023)

Phase 1 trial of ADI-PEG20 plus cisplatin in patients with pretreated metastatic melanoma or other advanced solid malignancies
por: Yao, Shuyang, et al.
Publicado: (2021)

Innovations in Extractive Phases for In-Tube Solid-Phase Microextraction Coupled to Miniaturized Liquid Chromatography: A Critical Review
por: Ponce-Rodríguez, Henry Daniel, et al.
Publicado: (2020)

Asunercept as an innovative therapeutic approach for recurrent glioblastoma and other malignancies
por: Krendyukov, Andriy, et al.
Publicado: (2019)

Innovative Therapeutic Approaches in Primary Cutaneous B Cell Lymphoma
por: Lang, Claudia C. V., et al.
Publicado: (2020)

Editorial: Innovative Therapeutic and Vaccine Approaches Against Respiratory Pathogens
por: Calzas, Cynthia, et al.
Publicado: (2019)

Innovative Therapeutic Approaches Based on Nanotechnology for the Treatment and Management of Tuberculosis
por: Kia, Pooneh, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_goupecl38kkpbj8jp5dfv3hv8g