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A novel blood-based assay for treatment monitoring of tuberculosis

OBJECTIVES: A novel 3-gene host transcriptional signature (GBP5, DUSP3 and KLF2) has been validated for tuberculosis (TB) treatment monitoring using laboratory-based RNA sequencing platforms. The signature was recently translated by Cepheid into a prototype cartridge-based test that can be run on th...

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Detalles Bibliográficos
Autores principales: Zimmer, Alexandra J., Schumacher, Samuel G., Södersten, Erik, Mantsoki, Anna, Wyss, Romain, Persing, David H., Banderby, Sara, Strömqvist Meuzelaar, Linda, Prieto, Jacqueline, Gnanashanmugam, Devasena, Khatri, Purvesh, Ongarello, Stefano, Ruhwald, Morten, Denkinger, Claudia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243580/
https://www.ncbi.nlm.nih.gov/pubmed/34193258
http://dx.doi.org/10.1186/s13104-021-05663-z