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Multivariate transcriptome analysis identifies networks and key drivers of chronic lymphocytic leukemia relapse risk and patient survival

BACKGROUND: Chronic lymphocytic leukemia (CLL) is an indolent heme malignancy characterized by the accumulation of CD5(+) CD19(+) B cells and episodes of relapse. The biological signaling that influence episodes of relapse in CLL are not fully described. Here, we identify gene networks associated wi...

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Detalles Bibliográficos
Autores principales: Griffen, Ti’ara L., Dammer, Eric B., Dill, Courtney D., Carey, Kaylin M., Young, Corey D., Nunez, Sha’Kayla K., Ohandjo, Adaugo Q., Kornblau, Steven M., Lillard, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243588/
https://www.ncbi.nlm.nih.gov/pubmed/34187466
http://dx.doi.org/10.1186/s12920-021-01012-y