A positive feedback loop between Periostin and TGFβ1 induces and maintains the stemness of hepatocellular carcinoma cells via AP-2α activation

BACKGROUND: Liver cancer stem cells (LCSCs) play key roles in the metastasis, recurrence, and chemotherapeutic resistance of hepatocellular carcinoma (HCC). Our previous research showed that the POSTN gene is closely related to the malignant progression and poor prognosis of HCC. This study aimed to...

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Detalles Bibliográficos
Autores principales: Chen, Gang, Wang, Yi, Zhao, Xin, Xie, Xiao-zai, Zhao, Jun-gang, Deng, Tuo, Chen, Zi-yan, Chen, Han-bin, Tong, Yi-fan, Yang, Zhen, Ding, Xi-wei, Guo, Peng-yi, Yu, Hai-tao, Wu, Li-jun, Zhang, Si-na, Zhu, Qian-dong, Li, Jun-jian, Shan, Yun-feng, Yu, Fu-xiang, Yu, Zheng-ping, Xia, Jing-lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243733/
https://www.ncbi.nlm.nih.gov/pubmed/34193219
http://dx.doi.org/10.1186/s13046-021-02011-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243733/
https://www.ncbi.nlm.nih.gov/pubmed/34193219
http://dx.doi.org/10.1186/s13046-021-02011-8

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