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Identification and functional study of GATA4 gene regulatory variants in atrial septal defects
BACKGROUND: Congenital heart disease (CHD) is the leading cause of mortality from birth defects. In adult CHD patients with successful surgical repair, cardiac complications including heart failure develop at late stage, likely due to genetic causes. To date, many mutations in cardiac developmental...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243876/ https://www.ncbi.nlm.nih.gov/pubmed/34193080 http://dx.doi.org/10.1186/s12872-021-02136-w |