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Identification and functional study of GATA4 gene regulatory variants in atrial septal defects

BACKGROUND: Congenital heart disease (CHD) is the leading cause of mortality from birth defects. In adult CHD patients with successful surgical repair, cardiac complications including heart failure develop at late stage, likely due to genetic causes. To date, many mutations in cardiac developmental...

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Detalles Bibliográficos
Autores principales: Fan, Dongchen, Pang, Shuchao, Chen, Jing, Shan, Jiping, Cheng, Qianjin, Yan, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243876/
https://www.ncbi.nlm.nih.gov/pubmed/34193080
http://dx.doi.org/10.1186/s12872-021-02136-w