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Spatial progression and molecular heterogeneity of IDH-mutant glioblastoma determined by DNA methylation-based mapping

Glioblastoma (GBM) is the most common malignant primary central nervous system (CNS) neoplasm in adults, and has an almost universally poor prognosis. Recently, an emphasis on genetic and epigenetic profiling has revealed a number of molecular features useful in the diagnostic and prognostic classif...

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Detalles Bibliográficos
Autores principales: Lyon, James F., Vasudevaraja, Varshini, Mirchia, Kanish, Walker, Jamie M., Corona, Robert J., Chin, Lawrence S., Tran, Ivy, Snuderl, Matija, Richardson, Timothy E., Viapiano, Mariano S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243907/
https://www.ncbi.nlm.nih.gov/pubmed/34193272
http://dx.doi.org/10.1186/s40478-021-01221-7