GC/MS(n) analysis of the crude reaction mixtures from Friedel–Crafts acylation: Unambiguous identification and differentiation of 3‐aroylbenzofurans from their 4‐ and 6‐regioisomers

RATIONALE: 3‐Aroylbenzofurans and their 2‐nitrophenyl derivatives constitute fundamental intermediates for the synthesis of target compounds with pharmaceutical properties. However, their preparation via the Friedel–Crafts acylation of 2‐phenylbenzofurans, using Lewis acid as catalyst, often leads t...

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Detalles Bibliográficos
Autores principales: Begala, Michela, Mancinelli, Michele, Quezada, Elias, Delogu, Giovanna Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244086/
https://www.ncbi.nlm.nih.gov/pubmed/33733542
http://dx.doi.org/10.1002/rcm.9082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244086/
https://www.ncbi.nlm.nih.gov/pubmed/33733542
http://dx.doi.org/10.1002/rcm.9082

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