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Contribution of genetic and epigenetic changes to escape from X-chromosome inactivation
BACKGROUND: X-chromosome inactivation (XCI) is the epigenetic inactivation of one of two X chromosomes in XX eutherian mammals. The inactive X chromosome is the result of multiple silencing pathways that act in concert to deposit chromatin changes, including DNA methylation and histone modifications...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244145/ https://www.ncbi.nlm.nih.gov/pubmed/34187555 http://dx.doi.org/10.1186/s13072-021-00404-9 |