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HCP5, as the sponge of miR-1291, facilitates AML cell proliferation and restrains apoptosis via increasing PIK3R5 expression

BACKGROUND: Acute myeloid leukemia (AML) is recognized as a hematological neoplasm with heterogenetic cytology and short-term outcome. HCP5 has been proven to be related with the pathogenesis of AML. However, the underlying mechanism of HCP5 in AML remains unclear. METHODS: Clinical profiles of AML...

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Detalles Bibliográficos
Autores principales: Liu, Yan, Jing, Xue-Bing, Wang, Zhen-Cheng, Han, Qing-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244151/
https://www.ncbi.nlm.nih.gov/pubmed/34187569
http://dx.doi.org/10.1186/s40246-021-00340-5