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Effect of the KCa3.1 blocker, senicapoc, on cerebral edema and cardiovascular function after cardiac arrest — A randomized experimental rat study
AIM: Formation of cerebral edema and cardiovascular dysfunction may worsen brain injury following cardiac arrest. We hypothesized that administration of the intermediate calcium-activated potassium (KCa3.1) channel blocker, senicapoc, would reduce cerebral edema and augment mean arterial pressure in...
Autores principales: | Hansen, Frederik Boe, Secher, Niels, Mattson, Thomas, Løfgren, Bo, Simonsen, Ulf, Granfeldt, Asger |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244250/ https://www.ncbi.nlm.nih.gov/pubmed/34223371 http://dx.doi.org/10.1016/j.resplu.2021.100111 |
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