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Structural basis of elongation factor 2 switching

Archaebacterial and eukaryotic elongation factor 2 (EF-2) and bacterial elongation factor G (EF-G) are five domain GTPases that catalyze the ribosomal translocation of tRNA and mRNA. In the classical mechanism of activation, GTPases are switched on through GDP/GTP exchange, which is accompanied by t...

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Detalles Bibliográficos
Autores principales: Fenwick, Michael K., Ealick, Steven E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244253/
https://www.ncbi.nlm.nih.gov/pubmed/34235467
http://dx.doi.org/10.1016/j.crstbi.2020.02.001