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Structures of teixobactin-producing nonribosomal peptide synthetase condensation and adenylation domains()

The recently discovered antibiotic teixobactin is produced by uncultured soil bacteria. The antibiotic inhibits cell wall synthesis of Gram-positive bacteria by binding to precursors of cell wall building blocks, and therefore it is thought to be less vulnerable to development of resistance. Teixoba...

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Detalles Bibliográficos
Autores principales: Tan, Kemin, Zhou, Min, Jedrzejczak, Robert P., Wu, Ruiying, Higuera, Raul A., Borek, Dominika, Babnigg, Gyorgy, Joachimiak, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244413/
https://www.ncbi.nlm.nih.gov/pubmed/34235466
http://dx.doi.org/10.1016/j.crstbi.2020.01.002