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Understanding the structural details of APOBEC3-DNA interactions using graph-based representations

Human APOBEC3 (A3; apolipoprotein B mRNA editing catalytic polypeptide-like 3) is a family of seven enzymes involved in generating mutations in nascent reverse transcripts of many retroviruses, as well as the human genome in a range of cancer types. The structural details of the interaction between...

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Detalles Bibliográficos
Autores principales: Ng, J.C.-F., Fraternali, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244423/
https://www.ncbi.nlm.nih.gov/pubmed/34235473
http://dx.doi.org/10.1016/j.crstbi.2020.07.001