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Disorder driven allosteric control of protein activity

Studies of protein allostery increasingly reveal an involvement of the back and forth order-disorder transitions in this mechanism of protein activity regulation. Here, we investigate the allosteric mechanisms mediated by structural disorder using the structure-based statistical mechanical model of...

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Detalles Bibliográficos
Autores principales: Tee, Wei-Ven, Guarnera, Enrico, Berezovsky, Igor N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244471/
https://www.ncbi.nlm.nih.gov/pubmed/34235479
http://dx.doi.org/10.1016/j.crstbi.2020.09.001