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Testing the length limit of loop grafting in a helical repeat protein

Alpha-helical repeat proteins such as consensus-designed tetratricopeptide repeats (CTPRs) are exceptionally stable molecules that are able to tolerate destabilizing sequence alterations and are therefore becoming increasingly valued as a modular platform for biotechnology and biotherapeutic applica...

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Detalles Bibliográficos
Autores principales: Ripka, Juliane F., Perez-Riba, Albert, Chaturbedy, Piyush K., Itzhaki, Laura S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244534/
https://www.ncbi.nlm.nih.gov/pubmed/34235484
http://dx.doi.org/10.1016/j.crstbi.2020.12.002