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Kinetics of tau aggregation reveals patient-specific tau characteristics among Alzheimer’s cases

The accumulation of tau aggregates throughout the human brain is the hallmark of a number of neurodegenerative conditions classified as tauopathies. Increasing evidence shows that tau aggregation occurs in a ‘prion-like’ manner, in which a small amount of misfolded tau protein can induce other, naïv...

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Detalles Bibliográficos
Autores principales: Kamath, Tarun V, Klickstein, Naomi, Commins, Caitlin, Fernandes, Analiese R, Oakley, Derek H, Frosch, Matthew P, Hyman, Bradley T, Dujardin, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244646/
https://www.ncbi.nlm.nih.gov/pubmed/34222869
http://dx.doi.org/10.1093/braincomms/fcab096