A novel miR1983-TLR7-IFNβ circuit licenses NK cells to kill glioma cells, and is under the control of galectin-1

Although pharmacological stimulation of TLRs has anti-tumor effects, it has not been determined whether endogenous stimulation of TLRs can lead to tumor rejection. Herein, we demonstrate the existence of an innate anti-glioma NK-mediated circuit initiated by glioma-released miR-1983 within exosomes,...

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Detalles Bibliográficos
Autores principales: Shah, Diana, Comba, Andrea, Faisal, Syed M., Kadiyala, Padma, Baker, Gregory J., Alghamri, Mahmoud S., Doherty, Robert, Zamler, Daniel, Nuñez, Gabriel, Castro, Maria G., Lowenstein, Pedro R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244780/
https://www.ncbi.nlm.nih.gov/pubmed/34249474
http://dx.doi.org/10.1080/2162402X.2021.1939601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244780/
https://www.ncbi.nlm.nih.gov/pubmed/34249474
http://dx.doi.org/10.1080/2162402X.2021.1939601

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