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A CRISPR-based assay for the study of eukaryotic DNA repair onboard the International Space Station

As we explore beyond Earth, astronauts may be at risk for harmful DNA damage caused by ionizing radiation. Double-strand breaks are a type of DNA damage that can be repaired by two major cellular pathways: non-homologous end joining, during which insertions or deletions may be added at the break sit...

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Detalles Bibliográficos
Autores principales: Stahl-Rommel, Sarah, Li, David, Sung, Michelle, Li, Rebecca, Vijayakumar, Aarthi, Atabay, Kutay Deniz, Bushkin, G. Guy, Castro, Christian L., Foley, Kevin D., Copeland, D. Scott, Castro-Wallace, Sarah L., Alvarez Saavedra, Ezequiel, Gleason, Emily J., Kraves, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244870/
https://www.ncbi.nlm.nih.gov/pubmed/34191829
http://dx.doi.org/10.1371/journal.pone.0253403