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GSTP1 positive prostatic adenocarcinomas are more common in Black than White men in the United States

GSTP1 is a member of the Glutathione-S-transferase (GST) family silenced by CpG island DNA hypermethylation in 90–95% of prostate cancers. However, prostate cancers expressing GSTP1 have not been well characterized. We used immunohistochemistry against GSTP1 to examine 1673 primary prostatic adenoca...

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Detalles Bibliográficos
Autores principales: Vidal, Igor, Zheng, Qizhi, Hicks, Jessica L., Chen, Jiayu, Platz, Elizabeth A., Trock, Bruce J., Kulac, Ibrahim, Baena-Del Valle, Javier A., Sfanos, Karen S., Ernst, Sarah, Jones, Tracy, Maynard, Janielle P., Glavaris, Stephanie A., Nelson, William G., Yegnasubramanian, Srinivasan, De Marzo, Angelo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244883/
https://www.ncbi.nlm.nih.gov/pubmed/34191807
http://dx.doi.org/10.1371/journal.pone.0241934