Mineralocorticoid receptors dampen glucocorticoid receptor sensitivity to stress via regulation of FKBP5

Responding to different dynamic levels of stress is critical for mammalian survival. Disruption of mineralocorticoid receptor (MR) and glucocorticoid receptor (GR) signaling is proposed to underlie hypothalamic-pituitary-adrenal (HPA) axis dysregulation observed in stress-related psychiatric disorde...

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Detalles Bibliográficos
Autores principales: Hartmann, Jakob, Bajaj, Thomas, Klengel, Claudia, Chatzinakos, Chris, Ebert, Tim, Dedic, Nina, McCullough, Kenneth M., Lardenoije, Roy, Joëls, Marian, Meijer, Onno C., McCann, Katharine E., Dudek, Serena M., Sarabdjitsingh, R. Angela, Daskalakis, Nikolaos P., Klengel, Torsten, Gassen, Nils C., Schmidt, Mathias V., Ressler, Kerry J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244946/
https://www.ncbi.nlm.nih.gov/pubmed/34077736
http://dx.doi.org/10.1016/j.celrep.2021.109185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244946/
https://www.ncbi.nlm.nih.gov/pubmed/34077736
http://dx.doi.org/10.1016/j.celrep.2021.109185

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