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Protein Phosphatase 2B Dual Function Facilitates Synaptic Integrity and Motor Learning

Protein phosphatase 2B (PP2B) is critical for synaptic plasticity and learning, but the molecular mechanisms involved remain unclear. Here we identified different types of proteins that interact with PP2B, including various structural proteins of the postsynaptic densities (PSDs) of Purkinje cells (...

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Detalles Bibliográficos
Autores principales: Lin, Zhanmin, Wu, Bin, Paul, Maarten W., Li, Ka Wan, Yao, Yao, Smal, Ihor, Proietti Onori, Martina, Hasanbegovic, Hana, Bezstarosti, Karel, Demmers, Jeroen, Houtsmuller, Adriaan B., Meijering, Erik, Hoebeek, Freek E., Schonewille, Martijn, Smit, August B., Gao, Zhenyu, De Zeeuw, Chris I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8244972/
https://www.ncbi.nlm.nih.gov/pubmed/34021041
http://dx.doi.org/10.1523/JNEUROSCI.1741-20.2021