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In vitro engineering of a bone metastases model allows for study of the effects of antiandrogen therapies in advanced prostate cancer
While androgen-targeted therapies are routinely used in advanced prostate cancer (PCa), their effect is poorly understood in treating bone metastatic lesions and ultimately results in the development of metastatic castrate resistant prostate cancer (mCRPC). Here, we used an all-human microtissue-eng...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245033/ https://www.ncbi.nlm.nih.gov/pubmed/34193425 http://dx.doi.org/10.1126/sciadv.abg2564 |