Maternal diabetes induces senescence and neural tube defects sensitive to the senomorphic rapamycin

Neural tube defects (NTDs) are the second most common structural birth defect. Senescence, a state of permanent cell cycle arrest, occurs only after neural tube closure. Maternal diabetes–induced NTDs are severe diabetic complications that lead to infant mortality or lifelong morbidity and may be li...

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Detalles Bibliográficos
Autores principales: Xu, Cheng, Shen, Wei-Bin, Reece, E. Albert, Hasuwa, Hidetoshi, Harman, Christopher, Kaushal, Sunjay, Yang, Peixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245044/
https://www.ncbi.nlm.nih.gov/pubmed/34193422
http://dx.doi.org/10.1126/sciadv.abf5089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245044/
https://www.ncbi.nlm.nih.gov/pubmed/34193422
http://dx.doi.org/10.1126/sciadv.abf5089

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