Development of novel benzofuran-isatin conjugates as potential antiproliferative agents with apoptosis inducing mechanism in Colon cancer

In the current work, a new set of carbohydrazide linked benzofuran-isatin conjugates (5a–e and 7a–i) was designed and synthesised. The anticancer activity for compounds (5b–d, 7a, 7b, 7d and 7g) was measured against NCI-55 human cancer cell lines. Compound 5d was the most efficient, and thus subject...

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Detalles Bibliográficos
Autores principales: Eldehna, Wagdy M., Salem, Rofaida, Elsayed, Zainab M., Al-Warhi, Tarfah, Knany, Hamada R., Ayyad, Rezk R., Traiki, Thamer Bin, Abdulla, Maha-Hamadien, Ahmad, Rehan, Abdel-Aziz, Hatem A., El-Haggar, Radwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245078/
https://www.ncbi.nlm.nih.gov/pubmed/34176414
http://dx.doi.org/10.1080/14756366.2021.1944127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245078/
https://www.ncbi.nlm.nih.gov/pubmed/34176414
http://dx.doi.org/10.1080/14756366.2021.1944127

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