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Nose-to-brain delivery of borneol modified tanshinone IIA nanoparticles in prevention of cerebral ischemia/reperfusion injury

Targeted treatment of cerebral ischemia/reperfusion injury (CIRI) remains a problem due to the difficulty in drug delivery across the blood–brain barrier (BBB). In this study, we developed Bo-TSA-NP, a novel tanshinone IIA (TSA) loaded nanoparticles modified by borneol, which has long been proved wi...

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Detalles Bibliográficos
Autores principales: Wang, Luting, Xu, Lin, Du, Junfeng, Zhao, Xiao, Liu, Mei, Feng, Jianfang, Hu, Kaili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8245080/
https://www.ncbi.nlm.nih.gov/pubmed/34180761
http://dx.doi.org/10.1080/10717544.2021.1943058